Stanislav Dikiy

Stanislav Dikiy

Postdoctoral Researcher at HHMI/MSKCC in the lab of Alexander Rudensky

Publications

Terminal differentiation and persistence of effector regulatory T cells essential for the prevention of intestinal inflammation

Published in BioRxiv, 2022

Using novel genetic tools, we characterized the transcriptional programs of distinct colonic effector Treg cell types.

Recommended citation: Dikiy, S et al. (2022). "Terminal differentiation and persistence of effector regulatory T cells essential for the prevention of intestinal inflammation" BioRxiv. https://doi.org/10.1101/2022.05.16.492030 http://dinkystas.github.io/files/treg_diff.pdf

A distal Foxp3 enhancer enables interleukin-2 dependent thymic Treg cell lineage commitment for robust immune tolerance

Published in Immunity, 2021

Here, we report that IL-2 - STAT5 signaling converged on an enhancer (CNS0) during Foxp3 induction.

Recommended citation: Dikiy, S; Li, J et al. (2021). "A distal Foxp3 enhancer enables interleukin-2 dependent thymic Treg cell lineage commitment for robust immune tolerance" Immunity. https://doi.org/10.1016/j.immuni.2021.03.020 http://dinkystas.github.io/files/cns0.pdf

Extrathymically Generated Regulatory T Cells Establish a Niche for Intestinal Border-Dwelling Bacteria and Affect Physiologic Metabolite Balance

Published in Immunity, 2018

pTreg cell deficiency led to heightened type 2 immune responses triggered by microbial exposure, which disrupted the niche of border-dwelling bacteria early during colonization.

Recommended citation: Campbell, C; Dikiy, S et al. (2018). "Extrathymically Generated Regulatory T Cells Establish a Niche for Intestinal Border-Dwelling Bacteria and Affect Physiologic Metabolite Balance" Immunity. https://doi.org/10.1016/j.immuni.2018.04.013 http://dinkystas.github.io/files/cns1.pdf