A distal Foxp3 enhancer enables interleukin-2 dependent thymic Treg cell lineage commitment for robust immune tolerance
Published in Immunity, 2021
Recommended citation: Dikiy, S; Li, J et al. (2021). "A distal Foxp3 enhancer enables interleukin-2 dependent thymic Treg cell lineage commitment for robust immune tolerance" Immunity. https://doi.org/10.1016/j.immuni.2021.03.020 http://dinkystas.github.io/files/cns0.pdf
Here, we report that IL-2 - STAT5 signaling converged on an enhancer (CNS0) during Foxp3 induction.
Dikiy, S; Li, J et al. (2021). "A distal Foxp3 enhancer enables interleukin-2 dependent thymic Treg cell lineage commitment for robust immune tolerance" Immunity. https://doi.org/10.1016/j.immuni.2021.03.020.